个人信息:
基本信息:王梅燕,女,博士,副教授,生物技术与食品科学学院,硕士研究生导师,国际知名杂志《Food Science and Human Wellness》青年编委。
教育背景:天津医科大学药理学博士(硕博连读)
获得荣誉:
1. 天津市“131”创新型人才培养工程第三层次人选;
2. 天津市高校“青年后备人才支持计划”人选;
3. 2023年度天津商业大学“市级大学生创新创业训练计划”项目优秀指导教师;
4. 2023年度“首届全国大学生化妆品创新大赛”优秀指导教师;
5. 2020、2024年度天津商业大学优秀本科毕业论文指导教师;
联系方式:wangmeiyan@tjcu.edu.cn
学科领域:
药食同源物质及其功能性成分(如陈皮及其黄酮类成分)的研究与开发
代表性论文:
[1] Wang, M.Y., Zhao, H., Wen, X., et al., Citrus flavonoids and the intestinal barrier: Interactions and effects. Comprehensive Reviews in Food Science and Food Safety, 2021, 20 (1): 225-251.(SCI 一区Top,IF=17.1,一作兼通讯)
[2] Meiyan Wang*, Yanlin Lu, Qifan Wu, Guomin Chen, Hui Zhao, Chi-Tang Ho, and Shiming Li*, Biotransformation and Gut Microbiota-Mediated Bioactivity of Flavonols. Journal of Agricultural and Food Chemistry, 2023,71(22): 8317-8331.(SCI 一区Top,IF=6.3,一作兼通讯)
[3] Meiyan Wang*, Jianying Li, Ting Hu, and Hui Zhao*, Metabolic fate of tea polyphenols and their crosstalk with gut microbiota. Food Science and Human Wellness, 2022,11 (3): 455-466.(SCI 二区,IF=8.3,一作兼通讯)
[4] Ting Hu, Peng Wu, Jianfeng Zhan, Weixin Wang, Junfeng Shen, Meiyan Wang*, Chi-Tang Ho, and Shiming Li*, Structure variety and its effects on biological activity of tea polysaccharides. Food Science and Human Wellness, 2022,11: 587-597.(SCI 二区,IF=8.3,通讯作者)
[5] Xiang Wen, Hui Zhao*, Liwen Wang, Liang Wang, Gang Du, Wenqiang Guan, Jianfu Liu, Xiaocang Cao, Xiaohua Jiang, Jingrui Tian, Meiyan Wang*, Chi-Tang Ho, and Shiming Li*, Nobiletin Attenuates DSS-Induced Intestinal Barrier Damage through the HNF4α-Claudin-7 Signaling Pathway. Journal of Agricultural and Food Chemistry, 2020. 68(16): p. 4641-4649.(SCI 一区Top,IF=6.3,通讯作者)
[6] Song, X.W., Wen, X., He, J.W., Zhao, H., Li, S.M., Wang, M.Y., Phytochemical components and biological activities of Artemisia argyi. Journal of Functional Foods, 2019. 52: p. 648-662.(IF=3.833,通讯作者)
[7] Wang, M.Y, Meng, D., Zhang, P., et al., Antioxidant Protection of Nobiletin, 5-Demethylnobiletin, Tangeretin, and 5-Demethyltangeretin from Citrus Peel in Saccharomyces cerevisiae. Journal of Agricultural and Food Chemistry, 2018. 66: p. 3155-3160.(SCI 一区Top,IF=6.3,第一作者)
[8] Wang, M.Y, Cheng, X.C, Chen, X.B., et al., Synthesis and biological evaluation of novel N-aryl-ω-(benzoazol-2-yl)-sulfanylalkanamides as dual inhibitors of α-glucosidase and protein tyrosine phosphatase 1B. Chemical Biology & Drug Design. 2018: p. 1-10.(IF=2.434,第一作者)
[9] Li, S.J., Yang, F.X., Wang, M.Y., et al., miR-378 Functions as an onco-miRNA by Targeting the ST7L/Wnt/β-catenin Pathway in Cervical Cancer. International Journal of Molecular Medicine, 2017. 40: p. 1047-1056.(IF=2.341,并列一作)
[10] Wang, M.Y, Jin, Y.Y, Wei, H.Y, et al., Synthesis, biological evaluation and 3D-QSAR studies of imidazolidine-2,4-dione derivatives as novel protein tyrosine phosphatase 1B inhibitors. European Journal of Medicinal Chemistry, 2015. 103: p. 91-104.(IF=3.982,排名第一)
科研项目:
1.主持 国家级自然科学基金青年项目 5-去甲川陈皮素上调肠道Muc2表达对溃疡性结肠炎的防治作用及分子机制研究
2.主持 天津市自然科学基金青年项目 陈皮有效成分5-去甲川陈皮素防治溃疡性结肠炎的分子机制研究
3.主持 校级科研启动基金 陈皮多甲氧基黄酮的抗氧活性研究
获奖成果:
主持国家自然科学基金青年项目1项、天津市自然科学基金青年项目1项、校级相关研究项目1项,另参与国家级与局级科研项目各1项。以第一作者或通讯作者身份发表在Journal of Agricultural and Food Chemistry,Comprehensive Reviews in Food Science and Food Safety等国际高水平杂志上发表多篇研究论文(包括一区4篇、二区1篇),累计影响因子达50以上,累计被引200多次;以第一发明人获授权国家发明专利1项(一种5-去甲川陈皮素及其制备方法与应用,CN 114432294 B)。